There is no reference sample of Bigfoot DNA to compare it with, so by definition, there cannot be a conclusive match.

Confirming it's Bigfoot How did the team definitively determine that the samples were from a Bigfoot? Did they take a blood or saliva sample from a living Bigfoot ? If so, how did they get that close, and why didn't they simply capture it or photograph it? If the samples were found in the wild, how do they know it wasn't left by another animal — or possibly even a hunter, hiker or camper who left human genetic material?
Previous alleged Bigfoot samples subjected to DNA analysis have been deemed "unknown" or "unidentified." However, "unknown" or "unidentified" results do not mean "Bigfoot." There are many reasons why a DNA sample might come back unknown, including that it was contaminated or too degraded by environmental conditions. Or it could simply mean that the animal it came from was not among the reference samples that the laboratory used for comparison. There is no reference sample of Bigfoot DNA to compare it with, so by definition, there cannot be a conclusive match.
Ketchum also issued a statement requesting that the U.S. government immediately recognize Bigfoot as "an indigenous people and immediately protect their human and Constitutional rights against those who would see in their physical and cultural differences a 'license' to hunt, trap, or kill them." Since no Bigfoot has ever been hunted, trapped or killed, it's not clear that the creatures — if they exist — require any special federal protection.
Ketchum's is not the only genetics-based project intended to find Bigfoot. Earlier this year, researchers from Oxford University and the Lausanne Museum of Zoology announced they were collecting samples of alleged Bigfoot and Yeti hair for genetic identification. Oxford geneticist Bryan Sykes collected materials from the public from May through September, and is currently conducting DNA analysis. Once the results are in, he plans to submit his results to a peer-reviewed scientific journal.
If Ketchum has the definitive proof she claims, the world will soon know about it, and Bigfoot will be proven once and for all. On the other hand, if the evidence never appears, or is inconclusive and flawed, the search will continue.

Benjamin Radford is deputy editor of Skeptical Inquirer science magazine and author of six books, including Tracking the Chupacabra and Scientific Paranormal Investigation: How to Solve Unexplained Mysteries. His website is www.BenjaminRadford.com.